Changes in Proteinuria and the Risk of Myocardial Infarction in People with Diabetes or Prediabetes: A Prospective Cohort Study at BMIMS, Pawapuri, Nalanda

Authors

  • Aditya Prakash Department of Emergency Medicine, Bhagwan Mahavir Institute of Medical Sciences, Pawapuri, Nalanda, Bihar, India
  • Dhananjay Prasad Department of Emergency Medicine, Bhagwan Mahavir Institute of Medical Sciences, Pawapuri, Nalanda, Bihar, India
  • Rashmi Kumari Department of Medicine, Bhagwan Mahavir Institute of Medical Sciences, Pawapuri, Nalanda, Bihar, India
  • Rashmi Sinha Department of Medicine, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India

DOI:

https://doi.org/10.30750/ijpbr.14.2.44

Keywords:

Proteinuria, myocardial infarction, monitoring, endothelial dysfunction, prediabetes.

Abstract

Background: Proteinuria is a reliable indicator of endothelial dysfunction and cardiovascular risk. Its advancement or regression may affect the incidence of myocardial infarction (MI), particularly in people with diabetes or prediabetes.
Methods: This prospective cohort research tracked 120 patients with diabetes or prediabetes for 12 months. Patients were classified based on proteinuria changes (better, unchanged, or worsened). The incidence of myocardial infarction was reported. Student’s t-test and the Chi-square test were used in the statistical analysis.
Results: Worsening proteinuria was linked to a greater incidence of MI (18 cases) compared to the stable (8 cases) and better groups (5 cases) (p=0.002). Patients with worsening proteinuria showed a considerably higher cardiovascular risk (22%) than the other groups.
Conclusion: Proteinuria progression greatly raises the risk of myocardial infarction in diabetic and prediabetes patients. Monitoring and early intervention may help to lower the number of cardiovascular events.

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Published

2026-06-30

How to Cite

1.
Prakash A, Prasad D, Kumari R, Sinha R. Changes in Proteinuria and the Risk of Myocardial Infarction in People with Diabetes or Prediabetes: A Prospective Cohort Study at BMIMS, Pawapuri, Nalanda. IJPBR [Internet]. 2026Jun.30 [cited 2026Aug.9];14(02):244-7. Available from: https://www.ijpbr.in/index.php/IJPBR/article/view/1275

Issue

Vol. 14 No. 02 (2026): Indian Journal of Pharmaceutical and Biological Research

Section

Articles

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Copyright (c) 2026 Aditya Prakash, Dhananjay Prasad, Rashmi Kumari, Rashmi Sinha

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.